Agouti Related Protein (AgRP) is Upregulated in Cushing's Syndrome
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SHORT COMMUNICATION Full Title: Agouti related protein (AgRP) is upregulated in Cushing’s syndrome Short title: AgRP is upregulated in Cushing’s syndrome
Alpha melanocyte stimulating hormone (α-MSH) is an agonist at the melanocortin 3 (MC3-R) and melanocortin 4 (MC4-R) receptors. α-MSH stimulates corticosterone release from rat and human adrenal cells. Patients with Cushing’s syndrome have elevated levels of serum α-MSH. Agouti related protein (AgRP) is an endogenous antagonist at the MC3-R and MC4-R and is expressed in the rat adrenal cortex. A...
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ژورنال
عنوان ژورنال: Experimental and Clinical Endocrinology & Diabetes
سال: 2005
ISSN: 0947-7349,1439-3646
DOI: 10.1055/s-2005-872895