Agonistic-Antagonistic Actions of Clomiphene Citrate on PGF2 Fluctuations in Ovariectomized Rat Uterus
نویسندگان
چکیده
منابع مشابه
Immunohistochemical Study on the PCNA–Immunoreactivity in the Uterus of Rats Ovariectomized or Treated With Antiestrogen Clomiphene Citrate
PCNA reactivity was estimated for the luminal and glandular epithelium and for the stromal cells. Treatment of clomiphene citrate decreased the proliferation of the luminal epithelial cell and stromal cells to the same extent as ovariectomy. In both of these groups, the proportion of anti–PCNA positive cells in the glandular epithelium was significantly higher than in the luminal epihelium and ...
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Clomiphene citrate is a white to pale yellow, essentially odorless, crystalline powder. It is freely soluble in methanol; soluble in ethanol; slightly soluble in acetone, water, and chloroform; and insoluble in ether. CLOMID is a mixture of two geometric isomers [cis (zuclomiphene) and trans (enclomiphene)] containing between 30% and 50% of the cis-isomer. Each white scored tablet contains 50 m...
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I A T p d m c vulatory dysfunction is one of the most common causes of eproductive failure in sub-fertile and infertile couples. In the bsence of other significant infertility factors, successful vulation induction often will restore normal fertility. Cloiphene citrate (CC) is the best initial treatment for the large ajority of anovulatory infertile women. The first clinical rial of CC therapy ...
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Ovary is a dynamic organ and generates excess amount of reactive oxygen species (ROS) during follicular growth, development, maturation and ovulation [1]. The increased level of ROS is scavenged by antioxidant systems [2]. A moderate increase of ROS could be beneficial for oocyte meiotic maturation and reproductive outcome [3-5]. Overproduction of ROS or depletion of enzymatic antioxidant syste...
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Background: Polycystic ovarian syndrome (PCOS) which is the most common form of anovulatory infertility affects 5-10% women of reproductive age. Clomiphene Citrate (C.C) is the first line treatment in infertile women entering intrauterine insemination (IUI) cycle. For C.C resistant patients the second approach is aromatase inhibitors such as Letrozole. The aim of this study is to compare the ef...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1992
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)39764-1