منابع مشابه
[Aging of brain].
老化とは単に年をとることをいうものではない ことは,幼 児が年を1歳 とったとき,老 化 した と い う人はいないことか ら明らかである。 しかし,壮 年期以後は年をとることを老化 した とい うことが多い。つまり,老 化は成熟期以後に 年を とることをい うわけである。 しかし,老 化の定義は難しく,百 人の学者が集 まれば百説あるといわれるほど,多 様である。定 義が定まらないことか ら,そ の機序 も明らかでは なく,当 然のことであるが防 ぐことも困難で あ る。 ,臨 床的面か らみると,“ 老化とは血管の 老化である” とい う言葉がきわめて適切なものと もいえる。た とえば,わ が国の死因の第二,第 三 を占めている心疾患,脳 血管障害の多 く,と くに 後者はほとんどが血管の老化,つ まり動脈硬化が 原因である疾患である。この両者で死因の40%以 上を占めていること...
متن کاملNutrients, Microglia Aging, and Brain Aging.
As the life expectancy continues to increase, the cognitive decline associated with Alzheimer's disease (AD) becomes a big major issue in the world. After cellular activation upon systemic inflammation, microglia, the resident immune cells in the brain, start to release proinflammatory mediators to trigger neuroinflammation. We have found that chronic systemic inflammatory challenges induce dif...
متن کاملNormal Aging of the brain
With the increase of the mean age of our populations, neurodegenerative diseases are becoming more and more important. This is also true for the early diagnosis of neurodegeneration and to allow for an early therapeutic intervention since degenerative diseases begin long before the patient experiences any symptoms. It can be months or years before clinical symptoms become obvious. Imaging with ...
متن کاملPathological aging of the brain
The distinction between normal vs. pathologic brain aging is not as clear cut as one might think. The prevalence of various pathologic findings that are causally linked to dementia increases with age, for example neurofibrillary tangles, amyloid plaques, and cerebro vascular disease. What makes the notion of distinguishing pathological from normal brain aging difficult is the fact that the same...
متن کاملInsulin and brain aging
The world's population is living much longer than in the past. It is crucial to find as many pathological factors that deteriorate the health condition and well-being of elderly people as possible. Loss of activity and functions over time is typical for elderly people. Aging affects brain function, metabolism and structure in different ways, and these effects have multiple etiologies. Cognitive...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: THE JOURNAL OF THE STOMATOLOGICAL SOCIETY,JAPAN
سال: 1989
ISSN: 1884-5185,0300-9149
DOI: 10.5357/koubyou.56.215