Aggregation of Blood Cells by 5-Hydroxytryptamine (Serotonin)

Aggregation of Blood Cells by 5-hydroxytryptamine (serotonin).

• A rapid, reproducible method of determiniEg the presence and relative amounts of adhesive and aggregated blood elements in the blood has recently been developed in this laboratory.The method involves measuring the pressure required to force blood at a constant rate through a standardized screen with multiple openings 20 micra square and 20 micra deep. This pressure has been named "screen nitr...

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Aggregation of Blood Cells by 5-Hydroxyiryptamine (Serotonin)

• A rapid, reproducible method of determiniEg the presence and relative amounts of adhesive and aggregated blood elements in the blood has recently been developed in this laboratory.The method involves measuring the pressure required to force blood at a constant rate through a standardized screen with multiple openings 20 micra square and 20 micra deep. This pressure has been named "screen nitr...

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The metabolism of serotonin (5-hydroxytryptamine).

Serotonin has assumed an important role as the focal point about which much current neurochemical investigation is centered. The fact that its methylated derivatives and some compounds which antagonize its action can cause hallucinations has even led to the hypothesis that some defect in the body’s ability to metabolize serotonin might be the underlying cause of schizophrenia. Yet relatively li...

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The Metabolism of Serotonin (5-Hydroxytryptamine)

Serotonin has assumed an important role as the focal point about which much current neurochemical investigation is centered. The fact that its methylated derivatives and some compounds which antagonize its action can cause hallucinations has even led to the hypothesis that some defect in the body’s ability to metabolize serotonin might be the underlying cause of schizophrenia. Yet relatively li...

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An assessment of platelet aggregation induced by 5-hydroxytryptamine.

A method of expressing platelet aggregation response after incubation relative to the response before incubation has been used in preference to using direct measurements, and some reasons are given for this choice. The effect of pre-incubating human platelets with reserpine has been compared with the effect of pre-incubation with 5-hydroxytryptamine (5HT). Reserpine inhibited 5HT-induced aggreg...

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Aggregation of Blood Cells by 5-Hydroxytryptamine (Serotonin)

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