Age-Related Tissue Stiffening: Cause and Effect
نویسندگان
چکیده
منابع مشابه
Age-related vascular stiffening: causes and consequences
Arterial stiffening occurs with age and is closely associated with the progression of cardiovascular disease. Stiffening is most often studied at the level of the whole vessel because increased stiffness of the large arteries can impose increased strain on the heart leading to heart failure. Interestingly, however, recent evidence suggests that the impact of increased vessel stiffening extends ...
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Age is the most significant risk factor for atherosclerosis; however, the link between age and atherosclerosis is poorly understood. During both aging and atherosclerosis progression, the blood vessel wall stiffens owing to alterations in the extracellular matrix. Using in vitro and ex vivo models of vessel wall stiffness and aging, we show that stiffening of extracellular matrix within the int...
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15 صفحه اولAge- and gender-related ventricular-vascular stiffening: a community-based study.
BACKGROUND Increases in vascular (Ea), ventricular systolic (Ees), and ventricular diastolic (Ed) elastance (stiffness) may contribute to the pathogenesis of heart failure (HF) with preserved ejection fraction (HFnlEF). The prevalence of HFnlEF increases strikingly with age, particularly in women. We hypothesized that ventricular-vascular stiffening may occur with age and be more pronounced in ...
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ژورنال
عنوان ژورنال: Advances in Wound Care
سال: 2013
ISSN: 2162-1918,2162-1934
DOI: 10.1089/wound.2011.0328