Age-Dependent Hepatic UDP-Glucuronosyltransferase Gene Expression and Activity in Children
نویسندگان
چکیده
منابع مشابه
Age-Dependent Hepatic UDP-Glucuronosyltransferase Gene Expression and Activity in Children
UDP-glucuronosyltransferases (UGTs) are important phase II drug metabolism enzymes. The aim of this study was to explore the relationship between age and changes in mRNA expression and activity of major human hepatic UGTs, as well as to understand the potential regulatory mechanism underlying this relationship. Using previously generated data, we investigated age-dependent mRNA expression level...
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ژورنال
عنوان ژورنال: Frontiers in Pharmacology
سال: 2016
ISSN: 1663-9812
DOI: 10.3389/fphar.2016.00437