Age, but not frailty status, is associated with postoperative opioid use in adults after hysterectomy
نویسندگان
چکیده
While prior studies show that age correlates with less opioid use after surgery, much is known regarding the influence of more nuanced assessments well-being. Frailty has emerged as a distinct measure function from chronological aging, and independently associated postoperative outcomes. We sought to explore association between patient frailty consumption following hysterectomy for all indications. conducted retrospective analysis patient-reported across 61 hospitals within single state 11/2017 02/2021. Our primary outcome was total consumed (in oral morphine equivalents [OME]) among patients who received an prescription postoperatively. Secondary outcomes were whether prescribed, if prescribed opioids consumed, refilled. exposure status, defined by modified index (mFi-5) criteria stratified into three groups based on score (0, 1, or >1). Other covariates included demographic/clinical attributes, procedural factors, events. Linear regression ages performed assess status consumption, adjusted covariates. repeated this in 65 years older. 12,388 underwent which 10,874 (87.8%) 5,524 (50.8%) had data. 1,917 (34.7%) mFi-5 at least one. Median OME 30 (IQR 0-75). 300 individuals (6.1% ) refill 1,348 (24.4%) prescribed. In multivariable analysis, older significantly (Ref<45: 45-64 old -10.749 [-13.577, -7.921] >=65 -26.966 [-33.451, -20.526]) while there no significant status. negatively receiving discharge (p=0.003). However, not refills (p=0.258) consuming (p=0.407). Within secondary those older, median 5 0-35). There again our linear model. (p=.031) but (p=.702) (p=0.066). results suggest age, hysterectomy. over old, ages. Evidence patterns can ensure appropriate population.
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ژورنال
عنوان ژورنال: American Journal of Obstetrics and Gynecology
سال: 2023
ISSN: ['1097-6868', '0002-9378', '1085-8709']
DOI: https://doi.org/10.1016/j.ajog.2022.12.108