منابع مشابه
QC and Affymetrix data
Quality Control (QC) assessment is a crucial first step in successful data analysis: before any comparisons can be performed it is necessary to check that there were no problems with sample processing, and that arrays are of sufficient quality to be included in a study. The Affymetrix platform has a collection of QC metrics and accompanying guidelines that aid the identification of problematic ...
متن کاملAppendix A: Affymetrix U95A Experiment
This is a subset of Affymetrix data that was used to develop the MAS 5.0 algorithm, which generates gene expression intensities values from the 16 perfect match (PM) and mismatch (MM) probe pairs. This dataset was created by Affymetrix and is publicly available at their web site www.affymetrix.com; search on the phrase “Latin square data” to find the link to the page containing a description of...
متن کاملAnalysis of Affymetrix Exon Arrays
Exon arrays enable the monitoring of expression on a more fine-grained level than conventional 3' arrays. By targeting single exons alternative splicing events can be detected. However, the increased amount of data resulting from the denser coverage of the transcribed regions gives rise to new challenges in data analysis compared to 3' arrays. One must carefully decide which probes are consider...
متن کاملNetAffx: Affymetrix probesets and annotations
NetAffx (http://www.affymetrix.com) details and annotates probesets on Affymetrix GeneChip microarrays. These annotations include (i) static information specific to the probeset composition; (ii) sequence annotations extracted from public databases; and (iii) protein sequence-level annotations derived from public domain programs, as well as libraries of hidden Markov models (HMMs) developed at ...
متن کاملAffymetrix Solutions for Cancer Analysis
· Copy Number/LOH experiments to identify tumor suppressor genes and oncogenes · Expression analysis to identify phenotypic changes in tumor cells · Tumor classification based on expression or LOH clustering · Clinical stratification based on LOH or expression patterns to predict therapeutic outcomes · Mitochondrial mutation detection as an early indicator of cancer genesis A F F Y M E T R I X ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Biotechnology
سال: 2000
ISSN: 1087-0156,1546-1696
DOI: 10.1038/82281