Aetiopathology of canine hepatitis in Kerala

Hepatitis in dogs could be due to infectious, toxic or metabolic causes. Among infectious causes, leptospira, canine adenovirus (CAV 1) and babesia are responsible at varying levels, depending on the local geo-climatic conditions. This study, conducted 40 with clinical signs of hepatitis Thrissur, Kerala, revealed occurrence 2.5 per cent (1/40) for CAV 1, 20 (8/40) leptospirosis 22.5 (9/40) babesiosis. The aetiologies were confirmed by polymerase chain reaction (PCR) targeting E3 gene microscopic agglutination test (MAT) peripheral blood smear examination Haematological profile 1 infected animals thrombocytopaenia, lymphopaenia, monocytopaenia granulocytosis. Serum biochemical analysis divulged elevated alanine aminotransferase (ALT), alkaline phosphatase (ALP), aspartate (AST), total bilirubin creatinine, decreased protein albumin. Significant decrease volume packed red cells (VPRC), haemoglobin (Hb) erythrocyte count (TEC), significant increase leukocyte (TLC) evident positive leptospirosis. ALP, AST urea nitrogen (BUN) protein. Severe anaemia thrombocytopenia mild leucocytosis ALP bilirubin, hypoproteinemia noticed