Aerobic metabolism underlies complexity and capacity

Aerobic metabolism underlies complexity and capacity.

The evolution of biological complexity beyond single-celled organisms was linked temporally with the development of an oxygen atmosphere. Functionally, this linkage can be attributed to oxygen ranking high in both abundance and electronegativity amongst the stable elements of the universe. That is, reduction of oxygen provides for close to the largest possible transfer of energy for each electr...

Effect of Intravenous Iron on Aerobic Capacity and Iron Metabolism in Elite Athletes.

PURPOSE Iron-deficient athletes are often treated with long-term, low-dose iron therapy. Such treatments may be efficacious in correcting iron deficiency; however, the effect on acute and chronic iron metabolism and subsequent endurance capacity is less clear. METHODS Fifteen national and international standard runners were identified as iron deficient nonanemic (IDNA) and assigned to either ...

Pioglitazone improves whole‐body aerobic capacity and skeletal muscle energy metabolism in patients with metabolic syndrome

AIMS/INTRODUCTION Low aerobic capacity is a strong and independent predictor of all-cause mortality in patients with metabolic syndrome (MetS). Here, we investigated the effects of pioglitazone treatment on whole-body aerobic capacity and skeletal muscle energy metabolism in MetS patients. MATERIALS AND METHODS A total of 14 male patients with MetS received oral pioglitazone 15 mg/day for 4 m...

Acclimation capacity underlies susceptibility to climate change.

Recent reports have presented meta-analyses of global biological impacts of climate change (1, 2). However, there is debate as to the level of confidence ascribed to the certainty that global climate change has caused the observed biological changes (3). Two important considerations in the assessment of how climate change will impact organisms are (i) how close organisms are to their thermal li...

Complexity, Capacity, and Capture