Adverse Effects of Pertussis and Rubella Vaccines

Bordetella pertussis and pertussis vaccines.

Bordetella pertussis is a human-specific pathogen that causes whooping cough. The use of pertussis whole-cell vaccines in infants and toddlers led to decreased circulation of the bacterium in the child population and a marked decrease in the incidence of the disease. However, vaccine does not result in life-long immunity; indeed, the circulation of the bacterium has not been controlled in the a...

Pertussis Vaccines

s of references provided in the position paper and GRADE tables  Amirthalingam G, Andrews N, Campbell H, Ribeiro S, Kara E, Donegan K, et al. Effectiveness of maternal pertussis vaccination in England: an observational study. Lancet 2014 Oct 25; 384(9953):1521-1528. BACKGROUND: In October, 2012, a pertussis vaccination programme for pregnant women was introduced in response to an outbreak acro...

Bordetella pertussis polymorphism and pertussis vaccines.

The topic of the article by Bottero et al. (1) is an important one, a bacterial vaccine for a preventable disease, pertussis. Many articles have been published on the subject in the last 10 years (for a review, see reference 6). In their study, Bottero et al. neither followed the recommendations of consensus meetings nor used published nomenclature. Furthermore, they compared vaccines that cann...

Economic analyses of rubella and rubella vaccines: a global review.

OBJECTIVE To investigate whether the incorporation of rubella vaccine into immunization programmes in developing countries is economically justified. METHODS A MEDLINE search was conducted for articles published between 1970 and 2000 that dealt with economic analyses of rubella and rubella-containing vaccines. The Eastern Mediterranean, South-East Asia, and Africa regional Index Medicus datab...

Use of human diploid cell MRC - 5, for production of Measles and Rubella virus vaccines