Advancing Clinical Trials to Streamline Drug Development
نویسندگان
چکیده
منابع مشابه
Advancing Clinical Trials to Streamline Drug Development.
The last decade in oncology has been marked by the identification of numerous new potential cancer targets and even more agents designed to inhibit them. The matrix of new targets, new agents, and the companion diagnostics required to identify the right patient for the right drug has created a major challenge for the clinical trial process. This has been compounded by the addition of new immuno...
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while preclinical research answers basic questions about a drug’s safety, it is not a substitute for studies of ways the drug will interact with the human body. “clinical research” refers to studies, or trials, that are done in people 1,2. as the developers design the clinical study, they will consider what they want to accomplish for each of the different clinical research phases and begin the...
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Alzheimer's disease is the most common cause of dementia in elderly people. Research into Alzheimer's disease therapy has been at least partly successful in terms of developing symptomatic treatments, but has also had several failures in terms of developing disease-modifying therapies. These successes and failures have led to debate about the potential deficiencies in our understanding of the p...
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Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infections (LRTIs) in infants and children around the world, resulting in three million hospitalizations and several hundred thousand deaths annually, the vast majority of which occur in developing nations. Treatment options for RSV are limited, and efforts to produce a vaccine have been unsuccessful thus far. Giv...
متن کاملAdvancing the drug discovery and development process.
The current state of affairs in the drug discovery and development process is briefly summarized and then ways to take advantage of the ever-increasing fundamental knowledge and technical knowhow in chemistry and biology and related disciplines are discussed. The primary motivation of this Essay is to celebrate the great achievements of chemistry, biology, and medicine and to inform and inspire...
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ژورنال
عنوان ژورنال: Clinical Cancer Research
سال: 2015
ISSN: 1078-0432,1557-3265
DOI: 10.1158/1078-0432.ccr-15-0039