Advances in understanding glycosyltransferases from a structural perspective
نویسندگان
چکیده
منابع مشابه
Advances in understanding glycosyltransferases from a structural perspective
Glycosyltransferases (GTs), the enzymes that catalyse glycosidic bond formation, create a diverse range of saccharides and glycoconjugates in nature. Understanding GTs at the molecular level, through structural and kinetic studies, is important for gaining insights into their function. In addition, this understanding can help identify those enzymes which are involved in diseases, or that could ...
متن کاملUnderstanding Infertility: Psychological and Social Considerations from a Counselling Perspective
This article provides an overview of the psychological and social implications of infertility. After describing the evolution of current theoretical understanding in this area, it outlines typical emotional and gender-specific reactions as well as the impact of infertility on the concept of identity and loss. Key questions are presented that medical professionals can use in order to facilitate ...
متن کاملunderstanding infertility: psychological and social considerations from a counselling perspective
this article provides an overview of the psychological and social implications of infertility. after describing the evolution of current theoretical understanding in this area, it outlines typical emotional and gender-specific reactions as well as the impact of infertility on the concept of identity and loss. key questions are presented that medical professionals can use in order to facilitate ...
متن کاملPseudokinases from a structural perspective.
The catalytic (C) subunit of PKA was the first protein kinase structure to be solved, and it continues to serve as the prototype for the protein kinase superfamily. In contrast, by comparing many active and inactive kinases, we developed a novel 'spine' concept where every active kinase is composed of two hydrophobic spines anchored to a hydrophobic F-helix. The R-spine (regulatory spine) is dy...
متن کاملChemokines from a Structural Perspective
Chemokines are a family of small, highly conserved cytokines that mediate various biological processes, including chemotaxis, hematopoiesis, and angiogenesis, and that function by interacting with cell surface G-Protein Coupled Receptors (GPCRs). Because of their significant involvement in various biological functions and pathologies, chemokines and their receptors have been the focus of therap...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Current Opinion in Structural Biology
سال: 2014
ISSN: 0959-440X
DOI: 10.1016/j.sbi.2014.08.012