Advances in limb salvage treatment of osteosarcoma
نویسندگان
چکیده
منابع مشابه
Advances in limb salvage treatment of osteosarcoma
Osteosarcoma is the most common primary malignant bone tumor; its standard treatment includes neoadjuvant chemotherapy combined with surgery. Neoadjuvant chemotherapy has significantly improved the 5-year survival and limb salvage rates in osteosarcoma since the 1870s. The survival rate of patients with limb salvage was not inferior to that of amputees, and therefore, limb salvage has become th...
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many years ago the treatment of sarcoma was radiotherapy up to 2000-4000 rad. this treatment was very complicated, due to producing neoplasm after radiotherapy. by this method of treatment of osteosarcoma, the rate of survival became about 20% (two years). the second method of treatment was chemotherapy for a period of 2-5 weeks that amputation was performed afterwards. by chemotherapy, the rat...
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BACKGROUND Tumor prostheses currently give the best short- and medium-term results for limb-salvage reconstruction procedures in the treatment of bone tumors. However, in developing countries, the cost of a tumor prosthesis is beyond the reach of much of the population. We report the use of autoclaved tumor-bearing bone in 10 patients, as an affordable alternative to the use of prostheses. ME...
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A retrospective multi-institutional study of 227 patients with osteosarcoma of the distal end of the femur was done to compare rates of local recurrence, metastasis, and survival. Three cohorts of patients who had had either a limb-sparing procedure, an above-the-knee amputation, or disarticulation of the hip were compared. The results revealed prevalences of eight of seventy-three, nine of 115...
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THE JOURNAL OF BONE AND JOINT SURGERY G. Bacci, MD S. Ferrari, MD A. Longhi, MD C. Forni, RN M. Versari, MA Department of Chemotherapy S. Lari, MD Department of Anaesthesia M. Mercuri, MD D. Donati, MD 5th Ward of Orthopaedic Surgery F. Bertoni, MD Service of Anatomy and Pathology E. Pignotti, MA Service of Statistics of the Department of Musculoskeletal Oncology Rizzoli Orthopaedic Institute, ...
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ژورنال
عنوان ژورنال: Journal of Bone Oncology
سال: 2018
ISSN: 2212-1374
DOI: 10.1016/j.jbo.2017.11.005