Adult Fanconi syndrome and multiple myelomatosis
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چکیده
منابع مشابه
Adult Fanconi syndrome and multiple myelomatosis.
A case is described of a 59-year-old woman presenting with multiple renal tubular defects. The aminoaciduria was of a generalized type. When investigated initially the only feature of myelomatosis was urinary Bence-Jones protein. Two years later radiologically classical multiple myelomatosis developed and rapidly progressed to the patient's death nine months later.
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A case of adult Fanconi syndrome is described in which there was urinary excretion of kappa light chains. After 13 years the patient developed overt myeloma. She also developed an adenocarcinoma of the colon and an adenocarcinoma of the parathyroid gland. These findings are discussed in relation to the known association between adult Fanconi syndrome, renal damage, and myeloma.
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DAWSON, D. W., and JOHNSON, J. (1958): Anticonvulsants and Megaloblastic Anaemia, Brit. med. J., i, 397. GIRDWOOD, R. H., and LENMAN, J. A. R. (1956): Anaemia occurring During Primidone Therapy, Brit. med. J., i, 146. GOUGH, K., READ, A., MCCARTHY, C., and WATERS, A. (1963): Megaloblastic Anaemia due to Nutritional Deficiency of Folic Acid, Quart. J. Med. N.S., 32, 243. HAWKINS, C. F., and MEYN...
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MULTIPLE myelomata are uncommon endosteal tumours developing from the myeloblastic elements of the bone marrow. The ribs, sternum, clavicle, vertebral bodies, and pelvis are favourite sites; the skull is also frequently involved and the long bones may be affected, but never alone (Perkins, 1936). The disease has an insidious onset and is often only recognized late when multiple nodules appear o...
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Bear this disease in mind when treating pains of the limbs of an obscure and intractable character.' This was said by Thos. Blizard Curling, F.R.S., Surgeon to the London Hospital, to William Macintyre i00 years ago. The quotation is from the paper in which Macintyre published at his leisure in i850 the clinical history of a case which had been noted to have ' urine of high density containing m...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1969
ISSN: 0021-9746
DOI: 10.1136/jcp.22.4.414