Adult Apaf-1-Deficient Mice Exhibit Male Infertility
نویسندگان
چکیده
منابع مشابه
Bmi1 Deficient Mice Exhibit Male Infertility
Previous studies have demonstrated that the polycomb repressor Bmi1 is universally expressed in all types of testicular cells and might regulate the spermatogonia proliferation, however, it is unclear whether Bmi1 plays a critical role in maintaining normal male fertility in vivo. To answer this question, we first confirmed that Bmi1 is universally expressed in all types of testicular cells and...
متن کاملI-1: Surgical Treatment of Male Infertility
Male factor is the sole reason or a component for infertility in 20 and 30% of cases respectively. The management of the disease may be via medical or surgical treatment. The surgical approach is classified as techniques which improves sperm production and delivery in order to achieve spontaneous pregnancy or sperm retrieval techniques prior to assisted reproductive techniques (ART). Varicocele...
متن کاملMale infertility, impaired sperm motility, and hydrocephalus in mice deficient in sperm-associated antigen 6.
Gene targeting was used to create mice lacking sperm-associated antigen 6 (Spag6), the murine orthologue of Chlamydomonas PF16, an axonemal protein containing eight armadillo repeats predicted to be important for flagellar motility and stability of the axoneme central apparatus. Within 8 weeks of birth, approximately 50% of Spag6-deficient animals died with hydrocephalus. Spag6-deficient males ...
متن کاملMale infertility, impaired spermatogenesis, and azoospermia in mice deficient for the pseudophosphatase Sbf1.
Pseudophosphatases display extensive sequence similarities to phosphatases but harbor amino acid alterations in their active-site consensus motifs that render them catalytically inactive. A potential role in substrate trapping or docking has been proposed, but the specific requirements for pseudophosphatases during development and differentiation are unknown. We demonstrate here that Sbf1, a ps...
متن کاملP-1: Coenzyme Q10 and Male Infertility
Background: The aim of this study was to evaluate seminal plasma coenzyme Q10 levels and oxidative stress in patients with different types of male infertility. Materials and Methods: The study took place in the Department of Chemistry and Biochemistry, College of Medicine, Al-Nahrain University- Baghdad-Iraq from the period of November 2004 till July 2006. Sixty patients with male infertility w...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Developmental Biology
سال: 2000
ISSN: 0012-1606
DOI: 10.1006/dbio.1999.9585