Adrenomedullin signaling is necessary for murine lymphatic vascular development
نویسندگان
چکیده
منابع مشابه
Literature watch. Adrenomedullin signaling is necessary for murine lymphatic vascular development.
The lymphatic vascular system mediates fluid homeostasis, immune defense, and tumor metastasis. Only a handful of genes are known to affect the development of the lymphatic vasculature, and even fewer represent therapeutic targets for lymphatic diseases. Adrenomedullin (AM) is a multifunctional peptide vasodilator that transduces its effects through the calcitonin receptor-like receptor (calcrl...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 2008
ISSN: 0021-9738
DOI: 10.1172/jci33302