Adrenocortical Adenoma Producing 18-Hydroxycorticosterone
نویسندگان
چکیده
منابع مشابه
A Case of Virilizing Adrenocortical Adenoma
SUMMARY A 2/12 Year-old boy with IsoSexual Pseudoprecocious puberty due to a Virilizing Adrenocortical adenoma is presentecl, who was crronously treated as CAH for 9 months. Prevalence, clinical presentation, diagnosis and differential diagnosis of these tumors are discussed briefly.
متن کاملAltered responses of plasma 18-hydroxycorticosterone and aldosterone to angiotensin II and adrenocorticotropin in patients with a 18-hydroxycorticosterone-producing tumor.
Plasma 18-hydroxycorticosterone (18-OHB) and aldosterone responses to angiotensin II (AII) and ACTH were examined in 2 patients with a 18-OHB-producing tumor (18-OHBPT) versus those in 8 patients with a aldosterone-producing adenoma (APA), 7 patients with low renin essential hypertension (LREH) and 10 normal subjects. Plasma 18-OHB and aldosterone levels and the 18-OHB: aldosterone ratio were h...
متن کاملExpression of CYP11B2 in Aldosterone-Producing Adrenocortical Adenoma: Regulatory Mechanisms and Clinical Significance.
Aldosterone-producing adrenocortical adenoma (APA) is responsible for the majority of cases clinically diagnosed as primary aldosteronism. Aldosterone synthase (CYP11B2) is one of the enzymes that play essential roles in aldosterone synthesis and is involved in the pathogenesis of APA. Recent studies have demonstrated that various factors and regulators influence the expression and function of ...
متن کاملCoexistence of aldosterone-producing adrenocortical adenoma and pheochromocytoma in an ipsilateral adrenal gland.
A 40-year-old female, diagnosed as essential hypertension, demonstrated a 2 cm mass in left adrenal gland by computed tomography without abnormal endocrinological findings. (131)I-adosterol and (123)I-metaiodobenzylguanidine (MIBG) scintigraphy at 39 years of age showed no abnormal accumulation. Follow up (131)I-adosterol scintigraphy performed one year later showed apparently abnormal uptake a...
متن کاملEvaluation of the mineralocorticoid activity of 18-hydroxycorticosterone.
1. The mineralocorticoid activity of 18-hydroxycorticosterone (18-OH-B) has been compared with that of aldosterone by using human bioassay in vivo with measurement of rectal potential difference and urinary log 10 Na+/K+ ratio. 2. A log-linear relationship was found between maximum change in rectal potential difference and increasing doses of aldosterone. 3. No mineralocorticoid activity could ...
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ژورنال
عنوان ژورنال: International Journal of Urology
سال: 1996
ISSN: 0919-8172,1442-2042
DOI: 10.1111/j.1442-2042.1996.tb00582.x