Adrenergic neuron blocking agents: Mode of action of guanethidine
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چکیده
منابع مشابه
Some factors affecting the neuron blocking action of guanethidine, xylocholine, bretylium and debrisoquin.
The uptake of guanethidine (3.3×10-5 M), debrisoquin (8.4×10-4 M), bretyliun (5.0 10-4 M) and xylocholine (1.0×10-3 M) by adrenergic neuron was studied indirectly by testing the ability of noradrenaline (NA) regarding low temp. or sodium deprivation to prevent or reverse adrenergic neuron blocking action in the indirectly stimulated ...
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Sharma and Rajapurkar (~) while studying the actions of adrenergic neurone blocking drugs on intestinal peristalsis observed that bretyliurn and xylocholine in bigger doses produced a stimulant response on the longitudinal moveme-nts of guinea pig ileum where as guanethidine had no stimulant action (unreported observations). Those observations are in consonance witb tbe observations of Boura an...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1978
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)53092-x