Adrenal Cortical Insufficiency

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Congenital Adrenal Cortical Insufficiency with Virilism

This paper presents the case of a boy developing symptoms of adrenal insufficiency soon after birth, followed by unmistakable evidences of the changes in the development associated with androgens. Other reports bring out the fact that the picture of increased androgenic activity with or without adrenocortical insufficiency is associated with hyperplasia and persistence of the fetal (androgenic)...

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Two cases of adrenal hyperplasia with adrenal cortical insufficiency.

The adreno-genital syndrome in infancy is associated almost invariably with bilateral adrenal hyperplasia. The characteristic syndrome is a combination of hyperfunction of the genital hormones of the suprarenal, producing precocious virilism in males and pseudohermaphroditism in females, and hypofunction of the salt-water hormones resulting in an electrolyte imbalance of the Addisonian type. Gl...

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Adrenal insufficiency.

Adrenal insufficiency is the clinical manifestation of deficient production or action of glucocorticoids, with or without deficiency also in mineralocorticoids and adrenal androgens. It is a life-threatening disorder that can result from primary adrenal failure or secondary adrenal disease due to impairment of the hypothalamic-pituitary axis. Prompt diagnosis and management are essential. The c...

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Adrenal insufficiency.

Adrenal insufficiency is a life-threatening condition that occurs secondary to impaired secretion of adrenal glucocorticoid and mineralocorticoid hormones. This condition can be caused by primary destruction or dysfunction of the adrenal glands or impairment of the hypothalamic-pituitary-adrenal axis. In children, the most common causes of primary adrenal insufficiency are impaired adrenal ster...

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Adrenal insufficiency.

Adrenal insufficiency is caused by either primary adrenal failure (mostly due to autoimmune adrenalitis) or by hypothalamic-pituitary impairment of the corticotropic axis (predominantly due to pituitary disease). It is a rare disease, but is life threatening when overlooked. Main presenting symptoms such as fatigue, anorexia, and weight loss are non-specific, thus diagnosis is often delayed. Th...

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ژورنال

عنوان ژورنال: Deutsches Aerzteblatt Online

سال: 2013

ISSN: 1866-0452

DOI: 10.3238/arztebl.2013.0882