ADOLF GUSSEROW (1836-1906).

Dmd053405 1906..1913

Carbinol [4,49-(hydroxymethylene)dibenzonitrile] is the main phase 1 metabolite of letrozole, a nonsteroidal aromatase inhibitor used for endocrine therapy in postmenopausal breast cancer. We elucidated the contribution of UDP-glucuronosyltransferase (UGT) isoforms on the glucuronidation of carbinol. Identification of UGT isoforms was performed using a panel of recombinant human UGT enzymes. Ki...

Pierre Curie, 1859–1906

The year 2006 marked 100 years since the death of Pierre Curie. It is therefore appropriate that we remember his life and his work, which was cut short by his untimely death from an accident on the Pont Neuf, Paris, on April 19, 1906. He had already accomplished much during his life, both before the discovery of radium with Marie Curie, in work co-authored with his brother Jacques on piezoelect...

Adolf Gru$ nbaum on religious delusions

Gru$ nbaum claims it is possible that all belief in God is a delusion, meaning a false belief which is engendered by irrational psychological motives. I dispute this on the grounds that in many cases belief in God is engendered by purely cultural factors, and this is incompatible with its being engendered by psychological ones. Gru$ nbaum also claims that saying a culturally engendered belief c...

Adolf Hitler had post-encephalitic Parkinsonism.

Adolf Hitler had Parkinson symptoms in 1934, at age 45 years. He may have had transient symptoms in 1923, at age 34 years. Young-onset parkinsonism, during the 1920s, favored a diagnosis of post-encephalitic rather than idiopathic parkinsonism. Hitler had oculogyric crises, phenomena only associated with post-encephalitic parkinsonism. In addition, he had dystonic facial spasms, palilalia and a...

Christian A. Herter, 1906