Adiponectin Protein Exists in Aortic Endothelial Cells

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چکیده

منابع مشابه

Adiponectin Protein Exists in Aortic Endothelial Cells

AIMS Inflammation is closely associated with the development of atherosclerosis and metabolic syndrome. Adiponectin, an adipose-derived secretory protein, possesses an anti-atherosclerotic property. The present study was undertaken to elucidate the presence and significance of adiponectin in vasculature. METHODS AND RESULTS Immunofluorescence staining was performed in aorta of wild-type (WT) ...

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Aortic Endothelial Cells

Isolated, cultured arterial endothelial cells express an acetylcholine (ACh)-activated K current in addition to an inward rectifier current whose conductance Ls unaffected by ACh. The cholinergic K current is specifically blocked by atropine (1 /xM) and shows single saturation kinetics with ACh (halfmaximal stimulation 51 nM ACh). Unlike the cardiac muscarinic receptor-gated K channel, its stim...

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Bovine Aortic Endothelial Cells

As bstract. We examined the effect of bovine aortic endothelial cell culture supernatants upon the generation of procoagulant activity by human blood monocytes. Confluent endothelial monolayers were cultured for up to 96 h. At timed intervals, culture supernatants were collected and incubated for 5 h with lipopolysaccharide-stimulated human peripheral blood mononuclear cells. The procoagulant a...

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Receptor for advanced glycation end products involved in circulating endothelial cells release from human coronary endothelial cells induced by C-reactive protein

Objective(s): This study was designed to investigate the effect of receptor for advanced glycation end products (RAGE), S100A12 and C-reactive protein (CRP) on the release of circulating endothelial cells (CECs) from human coronary artery endothelial cells (HCAECs). Materials and Methods: HCAECs were cultured in increasing concentration of CRP (0, 12.5, 25, 50μg/ml) or S100A12 protein (0, 4, 1...

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Cultured Porcine Aortic Endothelial Cells

Hemodynamic shear stress alters the architecture and functions of vascular endothelial cells. We have previously shown that the synthesis of endothelin-1 (ET-1 ) in endothelial cells is increased by exposure to shear stress. Here we examined whether shear stress-induced alterations in cytoskeletal structures are responsible for increases in ET-1 synthesis in cultured porcine aortic endothelial ...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2013

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0071271