Adipolin, Chemerin, Neprilysin and Metabolic Disorders Associated with Obesity

Adipolin, neprilysin, and chemerin have pleiotropic properties; therefore, their concentrations may influence health complications associated with obesity. The study aimed to search the relationship between adipokine levels anthropometric metabolic parameters as well blood pressure values, taking into account of gender age. group consisted 88 people aged 30–60 years. It was found that concentration is positively correlated glycaemia in 120′ OGTT (rs = 0.412; p 0.030) obese women. There a negative correlation adipolin LDL-C serum −0.414; 0.044) individuals normal glucose tolerance positive triglyceridemia 0.333; 0.033) men. Moreover, high (above median values) were observed 3.79 times more frequently (OR 3.79; 95% CI: 1.03–13.91; 0.040) male population characterized by elevated triglyceride 1.7 mmol/L). In logistic regression analyses, we frequency plasma increases age (p 0.005) only BMI < 30 kg/m2. also shown studied adipokines are interrelated. neprilysin selected metabolism exponents.