Additive Phenotypes Underlie Epistasis of Fitness Effects
نویسندگان
چکیده
منابع مشابه
Polygenicity and Epistasis Underlie Fitness-Proximal Traits in the Caenorhabditis elegans Multiparental Experimental Evolution (CeMEE) Panel
Understanding the genetic basis of complex traits remains a major challenge in biology. Polygenicity, phenotypic plasticity, and epistasis contribute to phenotypic variance in ways that are rarely clear. This uncertainty can be problematic for estimating heritability, for predicting individual phenotypes from genomic data, and for parameterizing models of phenotypic evolution. Here, we report a...
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ژورنال
عنوان ژورنال: Genetics
سال: 2018
ISSN: 1943-2631
DOI: 10.1534/genetics.117.300451