Adaptive capacity: exploring the research frontier

Exploring the Next Frontier of Mouse Vision

Two studies in this issue of Neuron apply in vivo functional imaging techniques to map out and record from mouse extrastriate visual cortex. They find that distinct areas show hallmarks of processing for different types of visual input and provide a promising path forward to investigate how complex image analysis is performed in the mouse visual system.

Frontier Research in Economics

Pushing the Frontier: Exploring the African Web Ecosystem

It is well known that Africa’s mobile and fixed Internet infrastructure is progressing at a rapid pace. A flurry of recent research has quantified this, highlighting the expansion of its underlying connectivity network. However, improving the infrastructure is not useful without appropriately provisioned services to utilise it. This paper measures the availability of web content infrastructure ...

Exploring the Capacity of Simple Neural Networks

The application of neural networks in pattern recognition problems constitute some difficult problems like initialization, choosing the correct architecture etc. In this paper the problem of ”how do networks find non-linear solutions” is addressed. By examining the properties of a simple (one input and one output) multi layered perceptron with sigmoidal transfer functions we try to show in what...

Human Germline: A New Research Frontier

We recently elucidated the mechanism of human primordial germ cell (hPGC) specification and resetting of the epigenome for totipotency. The regulators of hPGC specification also initiate resetting of the epigenome, leading to a comprehensive erasure of DNA methylation, erasure of imprints and X reactivation in early hPGCs in vivo. These studies reveal differences with the mouse model, which are...