ADA 2020: Dapagliflozin may help reduce onset of type 2 diabetes
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منابع مشابه
Dapagliflozin (Farxiga) for Type 2 Diabetes Mellitus.
Because dapagliflozin has been shown to induce glycosuria, patients should be warned about the most common clinical sequelae of osmotic diuresis, hypotension, and hypoglycemia. Systolic blood pressure typically decreases by 2.3 to 5.6 mm Hg. However, hypotension is relatively uncommon (number needed to harm [NNH] = 337) and mainly affects older adults, patients on loop diuretics, and those with...
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Sodium-glucose co-transporter 2 inhibitors (SGLT2is) such as dapagliflozin, canagliflozin, and empagliflozin, are a promising new therapy in the treatment of type 2 diabetes mellitus (T2DM). SGLT2is can effectively reduce hyperglycemia thus improving glycemic control and they offer some beneficial effects on the cardiovascular (CV) system which can benefit patients with heart failure in additio...
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OBJECTIVE Dapagliflozin, a novel inhibitor of renal sodium-glucose cotransporter 2, allows an insulin-independent approach to improve type 2 diabetes hyperglycemia. In this multiple-dose study we evaluated the safety and efficacy of dapagliflozin in type 2 diabetic patients. RESEARCH DESIGN AND METHODS Type 2 diabetic patients were randomly assigned to one of five dapagliflozin doses, metform...
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Context The incidence of type 2 diabetes is increasing and has been associated with the Westernisation of dietary habits. The Mediterranean dietary pattern (Med diet) may be a way to reduce the incidence of type 2 diabetes. In a trial, it was shown to reduce the need for antidiabetic drugs in diabetic patients,1 and an epidemiological study suggested a lower incidence of diabetes with increasin...
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INTRODUCTION The study refined definitions of type 2 diabetes and prediabetes (Pre-/T2D) via its four-category outcome variable. Respondents were identified as Pre-/T2D on the basis of (a) doctor's diagnosis only (i.e., managed Pre-/T2D); (b) biomarker only (i.e., undiagnosed Pre-/T2D); or (c) both diagnosis and biomarker (i.e., unmanaged Pre-/T2D). The reference was Pre-/T2D not indicated. We ...
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ژورنال
عنوان ژورنال: Diabetes, Obesity and Metabolism Now
سال: 2020
ISSN: 2688-8939,2688-8939
DOI: 10.1002/doi2.00020