Acute stress-induced change in polysialic acid levels mediated by sialidase in mouse brain

Ascorbic Acid Diminishes Developmental Damages Induced by High Glucose in Mouse Preimplantation Emberyos in vitro

Reduction in Aluminum Induced Oxidative Stress by Meloxicam in Rat Brain

Background: Non-steroidal anti-inflammatory drugs (NSAID) have been associated with antioxidant property and have been shown to improve the circulating antioxidant status on daily dosing in different inflammatory conditions. The present study was conducted to investigate the antioxidant role of meloxicam in aluminum induced oxidative stress in rat brain. Methods: In the in vivo experiments, Spr...

Sialic Acid and Sialidase Activity in Acute Stroke

Stroke is a heterogeneous syndrome caused by multiple disease mechanisms, resulting in a disruption of cerebral blood flow with subsequent tissue damage. It is well known that erythrocytes have a large amount of sialic acid and could represent a model to investigate changes occurring in a pathology like stroke. The aim of this study was to investigate a possible relationship among erythrocyte m...

Artificial Polysialic Acid Chains as Sialidase-Resistant Molecular-Anchors to Accumulate Particles on Neutrophil Extracellular Traps

Neutrophils are involved in numerous immunological events. One mechanism of neutrophils to combat pathogens is the formation of neutrophil extracellular traps (NETs). Thereby, neutrophils use DNA fibers to form a meshwork of DNA and histones as well as several antimicrobial components to trap and kill invaders. However, the formation of NETs can lead to pathological conditions triggering among ...

Ursolic Acid Attenuates Oxidative Stress-mediated HCC induced by DEN

Hepatocellular carcinoma is a major malignancy world wide (Lodato et al., 2006). It is the fourth most common malignant tumor in the world (Lee et al., 2005) and is the second leading fatal disease in mainland China El-Serrag (2004). Chemical hepatocarcinogenesis is a favourite model in rat, to study the mechanism of biotransformation of a normal cell to malignant populations. Carcinogenesis is...