Acute Severe Cushing Syndrome: Not Always Ectopic Acth Syndrome
نویسندگان
چکیده
منابع مشابه
A rare case of Cushing syndrome by cyclic ectopic-ACTH.
ACTH-dependent Cushing syndrome (CS) due to ectopic ACTH production is most times difficult to manage. The identification of the source of ACTH may take many years. Surgery or chemotherapy for the primary tumor is not always possible. Control of Cushing symptoms is many times achieved using medication, or bilateral adrenalectomy in refractory cases. This case presents a Brazilian male who showe...
متن کامل[Ectopic ACTH syndrome].
Cushing症 候群 は慢性的なコルチゾール過剰症であ り,放 置すると脳血管障害,糖 尿病,感 染症などで死 亡する.し たがって,適 切な診断 と治療が重要である. 表1に 示すように,ACTH依 存性Cushing症 候群 に は脳下垂体のACTH産 生腫によるGushing病 と異所 性ACTH症 候群があ り,ACTH非 依存性Cushing 症候群 には副腎原発性病変,医 原性 によるCushing症 候群がある.中 で もGushing病 と異所性ACTH症 候 群の鑑別 は治療法の選択 と関連 して重要である.我 々 が経験 した異所性ACTH症 候群を紹介する. 【症例】64歳,女 性.1993年 頃か ら顔面,下 腿の浮 腫,し びれ感 と全身の疼痛(肩 甲部,胸 部,腰 背部) を自覚するようになったため某院に入院した.糖 尿病, 高血圧,骨 粗鬆症 と診断さ...
متن کاملEctopic ACTH syndrome.
Ectopic adrenocorticotropic secretion (EAS) is responsible for 12-17% of cases of Cushing's syndrome (CS) and covers a range of tumours, from undetectable benign lesions to widespread metastases. The syndrome is often associated with severe hypercortisolaemia, which aggravates the underlying condition. EAS requires a complete workup that includes the establishment of endogenous CS, diagnosis of...
متن کاملEctopic ACTH syndrome: clinicopathological correlations.
Ten out of 164 cases of bronchogenic carcinoma showed pathological evidence at necropsy of the ectopic ACTH syndrome. All occurred in association with oat-cell carcinoma, constituting 19% of that group. The pathological features consisted of adrenocortical hyperplasia confined to the zona fasciculata and Crooke's hyaline change in the pituitary. Immunoperoxidase stainable ACTH was detected in t...
متن کاملSevere Cushing’s syndrome and bilateral pulmonary nodules: beyond ectopic ACTH
Cushing's syndrome is a rare disease that results from prolonged exposure to supraphysiological levels of glucocorticoids. Severe and rapidly progressive cases are often, but not exclusively, attributable to ectopic ACTH secretion. Extreme hypercortisolism usually has florid metabolic consequences and is associated with an increased infectious and thrombotic risk. The authors report on a case o...
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ژورنال
عنوان ژورنال: AACE Clinical Case Reports
سال: 2018
ISSN: 2376-0605
DOI: 10.4158/ep171905.cr