Acute progression of the leukemic phase in mycosis fungoides and Sézary syndrome

Cutaneous T-cell lymphomas (CTCLs) are a heterogeneous group of skin neoplasms that vary in presentation, histology, and prognosis. The most common subtype is mycosis fungoides (MF), which can range presentation from patch or plaque stage to tumor stage.1 Early-stage MF typically entails limited disease, without any nodal extracutaneous involvement. Usually, it follows an indolent course, with normal life expectancy, although progression disease death occur subset patients.