Acute Inhaled Xylene Poisoning Confirmed by Methylhippuric Acid Urine Test
نویسندگان
چکیده
منابع مشابه
Acute Inhaled Xylene Poisoning Confirmed by Methylhippuric Acid Urine Test
Xylene is a commonly used toxic volatile organic solvent. Diagnosis of acute xylene poisoning is limited by the lack of a readily available analytic assay. Methylhippuric acid, a metabolite of xylene excreted in the urine, is used for biomonitoring occupational exposures to xylene. We report two cases of acute occupational poisoning from xylene inhalation suggested by determination of high urin...
متن کاملThin-layer chromatography of hippuric and m-methylhippuric acid in urine after mixed exposure to toluene and xylene.
The separation of hippuric and m-methylhippuric acid as toluene and m-xylene metabolites present in urine of people exposed simultaneously to toluene and xylene is described. Chloroform was used for hippuric and m-methylhippuric acid extraction. Satisfactory separation of these metabolites was obtained on TLC plates covered with silica gels and developed in chloroform acetic acid-water (4:1:1);...
متن کاملAbsorption of m-xylene vapours through the respiratory tract and excretion of m-methylhippuric acid in urine.
Absorption of m-xylene and excretion of m-methylhippuric acid were investigated under controlled conditions in ten volunteers aged 17-33 years. They were exposed to m-xylene vapours at concentrations of 100, 300, and 600 mg/m3. It was found that m-xylene vapour retained in the lungs tended to decrease at the end of the exposure. An exposure test was devised, based upon the results obtained duri...
متن کاملUrine Methyl Hippuric Acid Levels in Acute Pesticide Poisoning: Estimation of Ingested Xylene Volume and Association with Clinical Outcome Parameters
To determine the relationship between the oral ingestion volume of xylene and methyl hippuric acid (MHA) in urine, we measured MHA in 11 patients whose ingested xylene volume was identified. The best-fit equation between urine MHA and ingested amount of xylene was as follows: y (ingested amount of xylene, mL/kg) = -0.052x² + 0.756x (x = MHA in urine in g/g creatinine). From this equation, we es...
متن کاملAcute arsine poisoning confirmed by speciation analysis of arsenic compounds in the plasma and urine by HPLC-ICP-MS.
OBJECTIVES Arsine, a potent hemolytic agent, is widely used in the semiconductor industry. We report a case of arsine poisoning confirmed by arsenic speciation analysis in serum and urine that occurred in a recycling factory. CASE A male worker in his twenties noticed hematuria 3 h after finishing work and was admitted into our hospital 34 h later. Speciation analysis of arsenics in serum and...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Clinical Toxicology
سال: 2015
ISSN: 2161-0495
DOI: 10.4172/2161-0495.1000274