Acute Hypoxia Increases S100β Protein in Association with Blood Flow Redistribution away from Peripheral Circulations in Fetal Sheep
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چکیده
منابع مشابه
comparison of blood flow velocity changes in posterior cerebral artery measured with transcranial doppler sonography in migraineurs with visual aura and normal persons after photostimulation
چکیده ندارد.
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Experimental studies in animal models supporting protective effects on the fetus of melatonin in adverse pregnancy have prompted clinical trials in human pregnancy complicated by fetal growth restriction. However, the effects of melatonin on the fetal defense to acute hypoxia, such as that which may occur during labor, remain unknown. This translational study tested the hypothesis, in vivo, tha...
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Although the fetal cardiovascular defence to acute hypoxia and the physiology underlying it have been established for decades, how the fetal cardiovascular system responds to chronic hypoxia has been comparatively understudied. We designed and created isobaric hypoxic chambers able to maintain pregnant sheep for prolonged periods of gestation under controlled significant (10% O2) hypoxia, yield...
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Observations on mature fetal lambs delivered under chloralose anesthesia showed that variations in arterial blood gas tensions, caused by ventilation with gas mixtures of differing composition, produced considerable changes in regional systemic blood flows measured with a cannulated electromagnetic flowmeter. Partial asphyxia was associated with a rise in arterial pressure and a reduction in fe...
متن کاملCalcitonin gene-related peptide increases pulmonary blood flow in fetal sheep.
Calcitonin gene-related peptide (CGRP) may play a role in regulation of pulmonary vascular tone in adults. We set out to establish whether or not CGRP has any effect on the fetal pulmonary circulation. Hemodynamic effects of exogenous CGRP were studied in seven near-term fetal sheep. Single CGRP injections into left pulmonary artery (LPA), compared with acetylcholine, and five repeated CGRP inj...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 2005
ISSN: 0031-3998,1530-0447
DOI: 10.1203/01.pdr.0000169999.66157.c0