Acute Hypotensive Transfusion Reactions

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Washed RBCs prevent recurrent acute hypotensive transfusion reactions.

OBJECTIVES To examine whether a liver transplant patient, who was not taking an angiotensin-converting enzyme inhibitor and developed two episodes of hypotension with systolic pressure in the 50s within minutes of starting an RBC transfusion, may have had a disturbance in the production and metabolism of bradykinin and des-Arg(9)-BK. METHODS All patient information was obtained by reviewing t...

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Transfusion reactions.

Blood components are indicated in a wide variety of disease states. Although most transfusion therapies are administered uneventfully, there are a number of potential adverse transfusion reactions, some of which can assume serious dimensions. These reactions could occur during or even days after a transfusion. A brief description of the adverse effects of transfusion therapy has been outlined i...

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Febrile nonhemolytic transfusion reactions.

A. FNHTRs are reported in 0.5%–5% of all transfusions. B. FNHTRs are the most common complication of platelet transfusion. 1. Incidence ranges from 1.7% to 31%. 2. Higher incidences are seen in patients who have received multiple prior transfusions. C. Incidence may decrease with increased use of prestorage leukocytereduced blood products. D. Higher incidence of blood transfusion reactions occu...

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Hemolytic transfusion reactions

A hemolytic transfusion reaction (HTR) is the accelerated clearance or lysis of transfused red cells because of immunologic incompatibility. Although they may at times have similar clinical presentations, HTR is distinguished from autoimmune hemolysis or nonimmune causes of shortened survival of transfused red cells. HTR may occur when antigen-positive red cells are transfused to a patient with...

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Delayed hemolytic transfusion reactions.

Delayed hemolytic transfusion reactions continue to occur in spite of the use of all of the currently available techniques of antibody detection. Both low titers of the antibodies and dosage effects appear to contribute to the failure of detection. A rapid anamnestic response can occur with transfusion of the appropriate antigen. The clinical as well as the laboratory presentation of delayed he...

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ژورنال

عنوان ژورنال: Laboratory Medicine

سال: 2006

ISSN: 0007-5027,1943-7730

DOI: 10.1309/pcarybe0rvafkddk