Acute fatty liver of pregnancy and the microvesicular fat diseases.

Acute fatty liver of pregnancy and the microvesicular fat diseases.

How accurate are the Swansea criteria to diagnose acute fatty liver of pregnancy in predicting hepatic microvesicular steatosis?

REFERENCES 1. Lee MG, Muallem S. Pancreatitis: the neglected duct. Gut 2008;57:1037e40. 2. Venglovecz V, Rakonczay Z Jr, Ózsvári B, et al. Effects of bile acids on pancreatic ductal bicarbonate secretion in guinea pig. Gut 2008;57:1102e12. 3. Criddle DN, Murphy J, Fistetto G, et al. Fatty acid ethyl esters cause pancreatic calcium toxicity via inositol trisphosphate receptors and loss of ATP sy...

Acute Fatty Liver of Pregnancy Etiology

and fats—are used in anabolic reactions to synthesize necessary materials for the body’s cells and tissues (Table 1). Fats are categorized as saturated, monounsaturated, and polyunsaturated and are broken down further into short-, medium-, and longchain fats; the length is determined by the number of carbons attached to the molecule. Metabolism of fatty acids is a complex process requiring bile...

Idiopathic acute fatty liver of pregnancy.

A maternal survivor of idiopathic fatty liver, with the characteristic histological appearance on liver biopsy, is reported. Profound hypoglycaemia was the major complication in this patient and it is suggested that more attention should be given to the blood glucose in this disease. The consideration of future pregnancy in this patient is discussed.

Non-fatal acute fatty liver of pregnancy.

Four patients are described, admitted during a three-year period, who recovered from acute fatty liver of pregnancy; vomiting and jaundice were the main manifestations of the disease; coma and anuria were absent. During the same period, we observed one patient who died of acute fatty liver of pregnancy. This experience suggests that the non-fatal form of the disorder may be much commoner than t...