ACTN3 R577X genotypes associate with Class II and deepbite malocclusions
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چکیده
منابع مشابه
ACTN3 R577X genotypes associate with Class II and deepbite malocclusions.
INTRODUCTION α-Actinins are myofibril anchor proteins that influence the contractile properties of skeletal muscles. ACTN2 is expressed in slow type I and fast type II fibers, whereas ACTN3 is expressed only in fast fibers. ACTN3 homozygosity for the 577X stop codon (ie, changing 577RR to 577XX, the R577X polymorphism) results in the absence of α-actinin-3 in about 18% of Europeans, diminishes ...
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The R577X polymorphism at the ACTN3 gene has been associated with muscle strength, hypertrophy and athletic status. The X allele, which is associated with the absence of ACTN3 protein is supposed to impair performance of high force/velocity muscle contractions. The purpose of the present study was to investigate the association of the R577X polymorphism with the muscle response to resistance tr...
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ژورنال
عنوان ژورنال: American Journal of Orthodontics and Dentofacial Orthopedics
سال: 2014
ISSN: 0889-5406
DOI: 10.1016/j.ajodo.2014.07.021