Activity of Some Plant and Fungal Metabolites towards Aedes albopictus (Diptera, Culicidae)

Aedes albopictus (Skuse) is a widespread mosquito, vector of important human arboviruses, including Chikungunya, Dengue and Zika. It an extremely difficult species to control even for the onset resistances chemicals insecticides, therefore ecofriendly products are urgently needed. In this study, activity Amaryllidaceae alkaloids some their semisynthetic derivatives, 2-methoxy-1,4-naphthoquinone two analogues, cyclopaldic acid epi-epoformin on survival development Ae. larvae was evaluated. First-instar larval exposure 24 48 h acid, resulted in mortality mean per-centage 82.4 96.9 respectively; 1,2-O,O-diacetyllycorine 48h post-treatment caused 84.7% mortality. Larval pupal duration were proved decrease significantly when exposed N-methyllycorine iodide. The number third-instar surviving 2-methyl-1,4-naphthoquinone, 2-hydroxy-1,4-naphthoquinone lower than correspondent over time. This study indicated that 1,2-O,O’-diacetyllycorine, iodide, 1,4-naphthoquinone structural derivatives have good potential developing bioinsecticides mosquito programs. obtained results general interest due global importance seri-ous diseases such able spread.