Activity of Antibiotics in Chronic Granulomatous Disease Leukocytes
نویسندگان
چکیده
منابع مشابه
Degranulation of leukocytes in chronic granulomatous disease.
Quantitative chemical analyses of the subcellular distribution patterns for acid and alkaline phosphatase, beta glucuronidase and peroxidase were obtained for human peripheral blood leukocytes of four patients with chronic granulomatous disease (CGD). Five young adults with acute infections served as controls. The observations were made on fractions obtained by homogenization and centrifugation...
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Chronic granulomatous disease (CGD) is a rare inherited disorder characterized by inability of phagocytes to generate oxygen radicals needed for intracellular killing of phagocytic microorganisms. We report a 2.5-year-old Iranian female with multiple liver abscesses. She was admitted in surgical ward because of abdominal pain and fever for one month duration that had no response to conventio...
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C HRONIC GRANULOMATOUS DISEASE (CCD) is a genetic disorder characterized by chronic and recurrent pyogenic infections, with abscess and granuloma formation throughout the reticuloendothelial system. Patients’ leukocytes fail to demonstrate the increase in oxygen consumption, hexose monophosphate shunt activity, nitroblue tetrazolium reduction, and hydrogen peroxide formation which normally occu...
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The leukocytes of patients with chronic granulomatous disease (CGD) may be identified by their failure to reduce Nitro Blue Tetrazolium (NBT) during phagocytosis. This reaction, normally detected in the phagocytic vacuole, is absent or delayed in CGD monocytes and eosinophils as well as in neutrophils, even though sonicates of normal and CGD leukocytes contain equal activities of a cyanide inse...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1983
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-198311000-00016