Activities of Monomeric Insulin Analogs at Position A8 Are Uncorrelated with Their Thermodynamic Stabilities
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چکیده
منابع مشابه
Two isostructural explosive cocrystals with significantly different thermodynamic stabilities.
Cocrystallization is currently having a tremendous impact on pharmaceuticals and energetic materials (energetics) and is poised to make a significant mark on other fields such as non-linear optics, ferroelectrics, and organic electronics. In the energetics field the ability of cocrystallization to combine two known explosive compounds into a novel material with distinct properties presents an e...
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A. Ektarawong,1,* S. I. Simak,2 and B. Alling1,3 1Thin Film Physics Division, Department of Physics, Chemistry and Biology (IFM), Linköping University, SE-581 83 Linköping, Sweden 2Theoretical Physics Division, Department of Physics, Chemistry and Biology (IFM), Linköping University, SE-581 83 Linköping, Sweden 3Max-Planck-Institut für Eisenforschung GmbH, D-40237 Düsseldorf, Germany (Received ...
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Constrained ceramide analogs were designed and synthesized by binding terminal alcohol and amine of ceramide with additional carbonyl functional group as 3-acetyl (3), 3-propionyl (4), 3-benzoyl (5), and 3-hexadecanoyl-4-(1-hydroxyhexadec-2-enyl)-oxazolidin-2-ones (6). Compounds 4 and 5 showed potent antileukemic activities against human leukemia HL-60 cells with good correlation between cell d...
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It is has been demonstrated that the addition of small quantities of carbon nanotubes (CNTs) can dramatically improve thermal and mechanical properties of polymers [1-6]. In many cases, however, this enhancement of properties is limited by the degree to which the CNTs can be uniformly dispersed within the polymer matrix. This appears to be particularly true for flame retarding applications. In ...
متن کاملThermodynamic stabilities of three-way junction nanomotifs in prohead RNA.
The thermodynamic stabilities of four natural prohead or packaging RNA (pRNA) three-way junction (3WJ) nanomotifs and seven phi29 pRNA 3WJ deletion mutant nanomotifs were investigated using UV optical melting on a three-component RNA system. Our data reveal that some pRNA 3WJs are more stable than the phi29 pRNA 3WJ. The stability of the 3WJ contributes to the unique self-assembly properties of...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2001
ISSN: 0021-9258
DOI: 10.1074/jbc.m104634200