Active behaviours produced by antidepressants and opioids in the mouse tail suspension test
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منابع مشابه
Active behaviours produced by antidepressants and opioids in the mouse tail suspension test.
Most classical preclinical tests to predict antidepressant activity were initially developed to detect compounds that influenced noradrenergic and/or serotonergic activity, in accordance with the monoaminergic hypothesis of depression. However, central opioid systems are also known to influence the pathophysiology of depression. While the tail suspension test (TST) is very sensitive to several ...
متن کاملThe tail suspension test.
The tail-suspension test is a mouse behavioral test useful in the screening of potential antidepressant drugs, and assessing of other manipulations that are expected to affect depression related behaviors. Mice are suspended by their tails with tape, in such a position that it cannot escape or hold on to nearby surfaces. During this test, typically six minutes in duration, the resulting escape ...
متن کاملZinc deficiency induces behavioral alterations in the tail suspension test in mice. Effect of antidepressants.
BACKGROUND Recently, experimental zinc deficiency has been correlated with depression-like alterations in rodents. METHODS In the first part of present study, the time course of zinc deficient diet induced alterations in the tail suspension test (TST) in mice was investigated. In the second part, the effect of imipramine and escitalopram in control and zinc-deprived for 3 weeks mice was exami...
متن کاملPattern of c-Fos expression induced by tail suspension test in the mouse brain
The tail suspension test (TST) has been widely used as a screening assay for antidepressant drugs. However, the neural substrates underlying the stress response and antidepressant-like effect during the TST remain largely unknown despite the prevalence of this test. In the present study, we used immunohistochemistry to examine alterations in c-Fos expression as a measure of neuronal activity in...
متن کاملthe relationship between learners critical thinking ability and their performance in the reading sections of the tofel and ielts test
the study reflected in this thesis aims at finding out relationships between critical thinking (ct), and the reading sections of tofel and ielts tests. the study tries to find any relationships between the ct ability of students and their performance on reading tests of tofel and academic ielts. however, no research has ever been conducted to investigate the relationship between ct and the read...
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ژورنال
عنوان ژورنال: International Journal of Neuropsychopharmacology
سال: 2013
ISSN: 1469-5111,1461-1457
DOI: 10.1017/s1461145711001842