Activation of NMDA Receptors in Lumbar Spinothalamic Cells is Required for Ejaculation
نویسندگان
چکیده
منابع مشابه
A pivotal role of lumbar spinothalamic cells in regulation of ejaculation via intraspinal connections
different aspects, with ejaculation being the most rewarding. Ejaculation is a complex reflex controlled by a central pattern generator in the lumbosacral spinal cord, named the spinal ejaculation generator.1 This generator receives sensory inputs during mating via the dorsal penile nerve and triggers emission and expulsion of seminal fluids via projections to autonomic and motor neurons in the...
متن کاملA pivotal role of lumbar spinothalamic cells in the regulation of ejaculation via intraspinal connections.
INTRODUCTION A population of lumbar spinothalamic cells (LSt cells) has been demonstrated to play a pivotal role in ejaculatory behavior and comprise a critical component of the spinal ejaculation generator. LSt cells are hypothesized to regulate ejaculation via their projections to autonomic and motor neurons in the lumbosacral spinal cord. AIM The current study tested the hypothesis that ej...
متن کاملActivation of gastrin-releasing peptide receptors in the lumbosacral spinal cord is required for ejaculation in male rats.
INTRODUCTION Ejaculation is a complex reflex mediated by a spinal ejaculation generator located in the lumbosacral spinal cord and consisting of a population of lumbar spinothalamic (LSt) neurons. LSt neurons and their intraspinal axonal projections contain several neuropeptides, including gastrin-releasing peptide (GRP). AIM To test the hypothesis that GRP is critically involved in mediating...
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Activation of NMDA receptors (NMDARs) within the CNS represents a major signal for persistent alterations in glutamatergic signaling, such as long-term potentiation (LTP) and long-term depression. NMDARs are composed of a combination of NR1 and NR2 subunits, with distinct NR2 subunits imparting distinct characteristics on the receptor. One particular NR2 subunit, NR2A (NRepsilon1), has been pro...
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Background: Feeding behavior is regulated by a complex network which interacts via diverse signals from central and peripheral tissues. It is known dopaminergic and glutamatergic systems have crucial role on food intake regulation but scarce reports exist on their interaction in appetite regulation in broilers. OBJECTIVES: The present study was designed to examine the role of glutamatergic syst...
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ژورنال
عنوان ژورنال: The Journal of Sexual Medicine
سال: 2011
ISSN: 1743-6095
DOI: 10.1111/j.1743-6109.2010.02168.x