Activation of a differentiation-inducing protein by adenine and adenine containing nucleotides
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منابع مشابه
Adenosine Receptor by Adenine Nucleotides
Adenosine and adenine nucleotides shorten the action potential duration of atrial myocytes and activate a specific acetylcholine and adenosine receptor-operated potassium outward current referred to as IKACh,Ado The objective of this study was to determine whether adenine nucleotides shorten the action potential duration and increase IKAChAdo in guinea pig atrial myocytes by directly activating...
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It has been reported from different laboratories [l-4] that mitochondria are capable of binding ATP. However the exact magnitude of binding, and the relevance of this process to the mechanism of oxidative phosphorylation are still unknown, due to the extremely low amounts of bound nucleotides, and to some difficulties in carrying out the measurements. The key to clarification of this problem ha...
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Guanylate cyclase is regulated by adenine nucleotides in membranes of intestinal mucosal cells. Basal guanylate cyclase was activated about twofold by adenine nucleotides. Activation was specific for adenine, as compared with the pyrimidine nucleotides UTP and CTP. In addition, enzyme activation was obtained in the presence of saturating concentrations of GTP, the substrate for guanylate cyclas...
متن کاملProtein Modification by Adenine Propenal
Base propenals are products of the reaction of DNA with oxidants such as peroxynitrite and bleomycin. The most reactive base propenal, adenine propenal, is mutagenic in Escherichia coli and reacts with DNA to form covalent adducts; however, the reaction of adenine propenal with protein has not yet been investigated. A survey of the reaction of adenine propenal with amino acids revealed that lys...
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Extracellular ATP and its metabolites affect various cellular immune responses, including T cell function, but there are apparently conflicting reports concerning the effects of adenine nucleotides on T cells. For example, it has been reported that ATP-mediated activation of P2 receptor is involved in T cell activation; activation of adenosine receptors suppresses T cell function; and 1 mM ATP ...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1971
ISSN: 0014-5793
DOI: 10.1016/0014-5793(71)80182-5