Action of Thyroid and Antithyroid Preparations.
نویسندگان
چکیده
منابع مشابه
Thyroid and Antithyroid Drugs
Three hormones, thyroxine (3,5,3 ,5 -tetraiodothyronine, or T4), triiodothyronine (3,5,3 -triiodothyronine, or T3), and calcitonin (see Chapter 66) are secreted by the thyroid gland. The hormones T4 and T3 are iodinecontaining amino acid derivatives and are unique in that they have no discrete target tissue. Every tissue in the body is affected in some way by thyroid hormones, and almost all ce...
متن کاملAntithyroid action of tetraethylthiuram disulfide.
Tetraethylthiuram disulfide (Antabuse) has been demonstrated to be clinically useful in treating alcoholism (1). The compound has been shown to inhibit the oxidation of acetaldehyde (2) and, further, to inhibit the action of rat liver xanthine oxidase to the extent of 71 per cent, and the succinoxidase system 100 per cent (3). Examination of the chemical structure of Antabuse indicates that it ...
متن کاملThe mechanism of the antithyroid action of iodide ion and of the aromatic thyroid inhibitors.
Two general classes of compounds interfere with the synthesis of the hormone thyroxine in the thyroid gland. These are the thiocarbamides and what will be referred to here as the “aromatic” antithyroid compounds. The present state of knowledge on the mechanism and locus of action of these substances has been reviewed recently (l-3). There appears to be general agreement that the thiocarbamides ...
متن کاملAntithyroid action of 3-amino-1,2,4-triazole.
It was first shown by Heim et al. (2, 3) that 1 hour after S-amino-l ,2,4-triazolel has been injected into rats, there is a marked inhibition of liver and kidney catalase, a lesser inhibition of liver peroxidase, and no inhibition of erythrocyte catalase activity. In view of this rather selective action towards tissue hydroperosidases, it seemed possible that aminotriazole should exhibit antith...
متن کاملCharacterization of thyroid function and antithyroid antibody tests among Saudis
OBJECTIVE To determine the reference intervals for thyroid function tests and the prevalence of thyroid autoimmunity in the Saudi population. METHODS A cross-sectional prospective study was conducted in King Khalid University Hospital, Riyadh, Saudi Arabia from January to June 2013. History and physical examination were obtained. Thyroid-stimulating hormone (TSH), free thyroxine (FT4), and ...
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ژورنال
عنوان ژورنال: Proceedings of the Royal Society of Medicine
سال: 1910
ISSN: 0035-9157
DOI: 10.1177/003591571000301213