Action of protoveratrine on the metabolism of cerebral cortex. 1. Unstimulated cerebral-cortex tissue*
نویسندگان
چکیده
منابع مشابه
Action of protoveratrine on the metabolism of cerebral cortex. 2. Electrically stimulated cerebral-cortex tissue.
متن کامل
Effect of paraoxon on the synaptosomal GABA uptake in rat hippocampus and cerebral cortex
Introduction: Paraoxon (the neurotoxic metabolite of organophosphorus (OP) insecticide, parathion) exerts acute toxicity by inhibition of acetylcholinesterase (AChE), leading to the accumulation of acetylcholine in cholinergic synapses and hence overstimulation of the cholinergic system. Since, reports on changes in the level of γ- amino butyric acid (GABA) during OP-induced convulsion have bee...
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Background: It has been suggested that organophosphates may inhibit gamma-aminobutyric acid (GABA) metabolism in synaptosomal preparations. In the present investigation, we have assessed the interaction between paraoxon and the GABA system at synaptic level. Methods: Synaptosomes were prepared from male Wistar rats (200-250 g). Cerebral cortex was dissected and homogenized, then centrifuged at ...
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Drug abuse has been claimed to cause the loss of neurons and reduction of volume in both the adult and developing brain. This study examined cortex volumes in cerebrum and cerebellum of male rats that were dependent on morphine using unbiased stereological counting methods and systematic random sampling technique. Our goal was to test whether short time exposure to morphine can affect the corte...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1955
ISSN: 0306-3283
DOI: 10.1042/bj0610068