Actinomycosis and Nocardiosis

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Actinomycosis and nocardiosis co-infection in chronic granulomatous disease.

Chronic granulomatous disease (CGD) is an inherited disease of the phagocyte NADPH oxidase system that causes defective production of toxic oxygen metabolites, leading to impaired bacterial and fungal killing, and recurrent life threatening infections; mostly by catalase producing organisms. Nocardiosis in CGD is well described, however actinomycosis is rare. We describe a patient of CGD with a...

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Endobronchial nocardiosis.

The presentation of a Nocardia infection is quite variable. We report a case of nocardiosis presenting as endobronchial obstruction with postobstructive pneumonia and atelectasis, in a patient with a low index of suspicion for bronchogenic carcinoma. Our report emphasizes the importance of considering the diagnosis of endobronchial nocardiosis in patients with endobronchial obstruction and a lo...

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Actinomycosis.

Actinomycosis is a rare, chronic, and slowly progressive granulomatous disease caused by filamentous Gram posi­ tive anaerobic bacteria from the Actinomycetaceae family (genus Actinomyces). It is often misdiagnosed because it can mimic other conditions such as malignancy and tuber­ culosis, and a high level of clinical suspicion is needed for an early diagnosis. However, it is readily treatable...

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Cerebral nocardiosis.

Localized and multisystem nocardiosis is an opportunistic disease that occurs commonly in immunocompromised patients. Rarely, it is also seen in immunocompetent individuals. The most common disease sites include lung, skin and central nervous system. We report a case of 73 years old man who is a known case of rheumatoid arthritis for more than 15 years and was on Methotrexate and Prednisolone. ...

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Cutaneous Nocardiosis

cutaneous inoculation. Primary cutaneous nocardiosis is more common, with incidence rates ranging from 5% to 24% in various countries like India, UK, and Spain [10-12]. A major problem is correct identification, as clinical presentation is not peculiar as well as histological findings, suggestive of an infective process, but not able to detect the microorganisms, unless a tissue culture has bee...

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ژورنال

عنوان ژورنال: American Journal of Clinical Pathology

سال: 1955

ISSN: 0002-9173,1943-7722

DOI: 10.1093/ajcp/25.1.2