Acquired Hemophilia A: A Frequently Overlooked Autoimmune Hemorrhagic Disorder
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چکیده
منابع مشابه
Acquired Hemophilia A: A Frequently Overlooked Autoimmune Hemorrhagic Disorder
Acquired hemophilia A (AHA) is a rare hemorrhagic disease in which autoantibodies against coagulation factor VIII- (FVIII-) neutralizing antibodies (inhibitors) impair the intrinsic coagulation system. As the inhibitors developed in AHA are autoantibodies, the disease may have an autoimmune cause and is often associated with autoimmune disease. Although acute hemorrhage associated with AHA may ...
متن کاملAcquired hemophilia A: an underdiagnosed, severe bleeding disorder.
Acquired hemophilia is a rare bleeding disorder caused by autoantibodies that inhibit coagulation factor VIII. In most cases, it manifests with severe, often life‑threatening bleeds. Acquired hemophilia may be idiopathic or secondary to another condition, most commonly other autoimmune disease or cancer. Treatment is directed to stop bleeding and eradicate inhibitory autoantibodies. Like in mos...
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OBJECTIVES To evaluate the clinical findings and outcomes of surgical treatment in patients with marginal entropion. MATERIALS AND METHODS Patients with impairment of the natural square-shaped eyelid margin morphology, anterior migration of mucocutaneous junction and mild lid inversion toward the ocular surface were diagnosed as having marginal entropion. Patients with shortened fornices, cic...
متن کاملAcquired Hemophilia A
Acquired hemophilia A is a rare but often life-threatening hemorrhagic disorder characterized by an auto antibody directed against coagulation factor VIII. Fifty per cent of cases are idiopathic whereas the remaining 50% are associated with pregnancy, autoimmune conditions, malignancies and drugs [1]. Acquired hemophilia is significantly rarer than the inherited form, affecting around 2 per mil...
متن کاملHemorrhagic pericardial effusion as the debut of acquired hemophilia in a chronic lymphocytic leukemia patient
BACKGROUND Acquired hemophilia A (AHA) is a rare bleeding disease caused by autoantibodies against factor VIII. Spontaneous bleeding symptoms usually affect the skin and muscle, while pericardial effusion is an extremely rare manifestation. In the elderly, anticoagulant treatment is frequent and bleeding symptoms are usually associated with this. CLINICAL FINDINGS We report a hemorrhagic peri...
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ژورنال
عنوان ژورنال: Journal of Immunology Research
سال: 2014
ISSN: 2314-8861,2314-7156
DOI: 10.1155/2014/320674