Acquired C3 deficiency in patients with alcoholic cirrhosis predisposes to infection and increased mortality.

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Acquired C3 deficiency in patients with alcoholic cirrhosis predisposes to infection and increased mortality.

BACKGROUND Acquired deficiencies of certain complement proteins and impaired opsonisation activity have been implicated in the pathogenesis of the increased susceptibility to infections of patients with alcoholic cirrhosis. METHODS Serum concentrations of C3 and C4, plasma concentrations of C3bc, C9, and the terminal C5b-9 complement complex (TCC), and haemolytic complement activity (classic ...

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ژورنال

عنوان ژورنال: Gut

سال: 1997

ISSN: 0017-5749

DOI: 10.1136/gut.40.4.544