Acid-soluble phosphate metabolism in nuclei from rat thymus gland

Metabolic properties of histones from rat liver and thymus gland.

1. The incorporation of (14)C-labelled amino acids into acid-extractable proteins from rat-liver and -thymus nuclei confirmed the existence of a protein component with a higher uptake than that into the major histone components. 2. This rapidly labelled component appeared to contain the thiol groups detectable in the acid extracts. 3. Histone f1 contained 1mol. of serine phosphate/mol. of mol.w...

The effects of x-irradiation on the incorporation of amino acids into proteins of nuclei from rat thymus gland.

There are inconsistencies in the reports of experiments on the effects of whole-body irradiation on protein synthesis. Some workers observed increases in synthetic activity soon after irradiation (Hevesy, 1949; Richmond, Altman & Salomon, 1951; Kay & Entenman, 1956; Butler, Cohn & Crathorn, 1957), others noticed no change (Abrams, 1951; Holmes & Mee, 1952; Killander, Ribbing, Ringertz & Richard...

Compensatory Hypertrophy of the Thymus Gland in the Rat

Previous experimental work concerning enlargement of the thymus has dealt mainly with the regeneration which follows partial or subtotal removal, or with the regeneration which follows transplantation. We planned our experiments to obtain evidence of uncomplicated hypertrophy by removing one lobe and studying the enlargement of the remaining lobe. Our results clearly indicate that such hypertro...

The metabolism of isolated rat-liver nuclei.

The investigations described in this paper were undertaken as a preliminary to the study of the biochemical changes in the nucleus of the rat-liver cell during the induction of liver cancer. Allfrey (1954) and Stern & Mirsky (1953) described the isolation in aqueous media of nuclei from the thymus gland of the calf. Such preparations in vitro incorporated glycine and other amino acids into nucl...

The Thymus Gland - ReadingSample