Acid degradation studies of 6-deoxyerythromycin A.
نویسندگان
چکیده
منابع مشابه
Acid degradation studies of 6-deoxyerythromycin A.
Erythromycin A (1), a well-established macrolide antibiotic, is unstable under acidic conditions. When administered orally, 1 is in equilibrium with its 8,9-anhydro-6,9-hemiketal and is simultaneously converted directly to the antibacterially inactive 6,9:9,12-spiroketal1}. A number of research groups in recent years have prepared new derivatives of erythromycin A by modification of the functio...
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UV degradation of deoxyribonucleic acid
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1993
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.46.698