Acetaldehyde dehydrogenase 2 SNP rs671 and susceptibility to essential hypertension in Mongolians: a case control study

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Acetaldehyde dehydrogenase 2 SNP rs671 and susceptibility to essential hypertension in Mongolians: a case control study.

Mongolians are known as heavy drinkers, and they have a high incidence of essential hypertension, which may be an associated pathology. We examined a possible association of essential hypertension and polymorphism of the aldehyde dehydrogenase 2 (ALDH2) gene in Mongolians from Inner Mongolia. Single nucleotide polymorphism rs671 of ALDH2 was detected by TaqMan PCR in 91 essential hypertensive p...

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Positive association between ALDH2 rs671 polymorphism and essential hypertension: A case-control study and meta-analysis

BACKGROUND AND OBJECTIVE Several studies have been conducted to examine the association between aldehyde dehydrogenase 2 family (ALDH2) rs671 polymorphism and essential hypertension (EH). However, the results remain inconsistent. This study aimed to clarify the association between ALDH2 rs671 polymorphism and EH susceptibility. METHODS One thousand and ninety-four cases and 1236 controls who ...

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ژورنال

عنوان ژورنال: Genetics and Molecular Research

سال: 2011

ISSN: 1676-5680

DOI: 10.4238/vol10-1gmr1056