Abstract P25. Hyberbaric Normothermic Perfusion Mitigates Reperfusion Injury in Porcine Vascular Composite Allotransplantation (VCA)
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چکیده
منابع مشابه
Abstract P25. Hyberbaric Normothermic Perfusion Mitigates Reperfusion Injury in Porcine Vascular Composite Allotransplantation (VCA)
PURPOSE: Patients undergoing autologous breast reconstruction are at high risk of perioperative venous thromboembolic events (VTE). The efficacy of chemoprophylaxis in decreasing VTE is well established but the timing of chemoprophylaxis remains controversial. Many surgeons are reluctant to initiate preoperative chemoprophylaxis due to concerns of bleeding. We compare the incidence of bleeding ...
متن کاملAbstract: Prevention of Ischemic-Reperfusion Injury and Chronic Rejection in a Porcine Vascularized Composite Allotransplantation Model
INTRODUCTION: Lipedema is a chronic disorder characterized by localized adiposity, typically isolated to the lower extremities (LEs). The interplay between the deposition of fatty tissue associated with lipedema and impairments of lymphatic flow remains unclear. The purpose of this study is to evaluate lymphoscintigraphic findings in patients with a clinical diagnosis of lipedema in order to be...
متن کاملHyperbaric Sub-Normothermic Ex-Vivo Perfusion Delays the Onset of Acute Rejection in a Porcine VCA Model.
INTRODUCTION: Vascularized composite allotransplantation (VCA) offers superior functional recovery following devastating maxillofacial and upper limb injuries compared to traditional reconstructive techniques. Here, we evaluate the efficacy of a novel sub-normothermic (SN) ex-vivo perfusion strategy using hyper-oxygenated University of Wisconsin (UW) solution to mitigate reperfusion injury (RI)...
متن کاملIschemia/reperfusion during normothermic perfusion.
INTRODUCTION Cold storage of organs for preservation and transplantation is reaching its limits especially with extended criteria for heart beating donors and donation after cardiac death. We will discuss recent findings and perspectives in normothermic kidney preservation. METHODS A literature review was performed from original articles and syntheses selected by the search engine PubMed. Key...
متن کاملHydrogen sulfide mitigates reperfusion injury in a porcine model of vascularized composite autotransplantation.
BACKGROUND Devastating extremity injuries are prevalent but often survivable on the modern battlefield. These complex injuries require advanced methods of reconstruction, involving prolonged ischemic periods and reperfusion injury. Using our group's validated porcine model of gracilis myocutaneous flap transplantation, this study demonstrates that an interim perfusion of hydrogen sulfide (H2S) ...
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ژورنال
عنوان ژورنال: Plastic and Reconstructive Surgery - Global Open
سال: 2017
ISSN: 2169-7574
DOI: 10.1097/01.gox.0000513399.50193.60