منابع مشابه
Ddi029 327..334
Erythropoietic protoporphyria (EPP) is an autosomal inherited disease of heme biosynthesis caused by a partial deficiency of the enzyme ferrochelatase. Patients with EPP show only 20–30% normal activity because of mutations in one of the alleles of the ferrochelatase gene. To clarify the molecular mechanisms of this low level of activity, we co-expressed human ferrochelatase carrying Hisand HA-...
متن کاملDmd059618 325..334
Pemetrexed, an anionic anticancer drug with a narrow therapeutic index, is eliminated mainly by active renal tubular secretion. The in vitro to in vivo extrapolation approach used in this work was developed to predict possible drug-drug interactions (DDIs) that may occur after coadministration of pemetrexed and nonsteroidal anti-inflammatory drugs (NSAIDs), and it included in vitro assays, risk...
متن کاملNpgrj_nn_2057 334..343
Estrogens have long been implicated in influencing cognitive processes, yet the molecular mechanisms underlying these effects and the roles of the estrogen receptors alpha (ERa) and beta (ERb) remain unclear. Using pharmacological, biochemical and behavioral techniques, we demonstrate that the effects of estrogen on hippocampal synaptic plasticity and memory are mediated through ERb. Selective ...
متن کاملC2ja10304d 327..334
An on-line solid-phase extraction method linked to inductively coupled mass spectrometry (ICP-MS) has been developed for the determination of low levels of uranium and thorium in environmental samples. The hyphenation of lab-on-valve (LOV) and multisyringe flow injection analysis (MSFIA), coupled to an ICP-MS, allows the simultaneous determination of thorium and uranium in different types of en...
متن کاملAap20765 334..339
Introduction: Total knee arthroplasty is associated with moderate to severe pain, and effective analgesia is essential to facilitate postoperative recovery. This retrospective cohort study examined the analgesic and rehabilitation outcomes associated with 48-hour continuous femoral nerve block, local infiltration analgesia, or local infiltration analgesia plus adductor canal nerve block. Method...
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ژورنال
عنوان ژورنال: Pediatric Critical Care Medicine
سال: 2018
ISSN: 1529-7535
DOI: 10.1097/01.pcc.0000537791.34250.81